The Influence of 50Hz Magentic Fields on Liver Function

Research Item – http://www.biophysicsnet.ro

Abstract. The present study has been conducted to evaluate the influence of different intensities of 50 Hz magnetic field on some liver function tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin, albumin and protein. The study also involved the effect of magnetic field on the oxidative state of the liver tissue. The study was conducted on about 80 Sparague-Dawely male rats of an average weight of 140–160 g. The exposure period was 2 hours/day for two weeks. The sera taken from control and exposed rats were also examined spectroscopically. The results showed an increase (p < 0.05) in the concentration of all investigated liver enzymes. Both bilirubin and aspartate aminotransferase were mostly affected with exposure (with a percentage > 90%), while albumin and alanine aminotransferase changed with about 11% and 22% respectively. The applied field also caused an increase in the liver lipid peroxidation and a decrease (p < 0.05) in glutathione concentration. Results consequently suggest that the redox potential of both glutathione (GSH/GSSG) and nicotinamide dinucleotide (NADH/NAD) are disturbed as a result of exposure. Precursors of NADH, as a result of its exhaustion, such as kynurenine, tyrosine and tryptophan, might be also affected.

Download Full Study

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s